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KMID : 0367020200320040374
Journal of Korean Academic of Adult Nursing
2020 Volume.32 No. 4 p.374 ~ p.384
Impact of Chronic Kidney Disease on Depression, Perceived Health, and Health-Related Quality of Life: Results from the Korea National Health and Nutrition Examination Survey in 2014 and 2016
Yoo Cheong-Sook

Kim Yun-Mi
Kim Hyun-Young
Abstract
Purpose: This study evaluated the impact of Chronic Kidney Disease (CKD) on depression, perceived health, and Health-Related Quality of Life (HRQOL) in community-dwelling adults.

Methods: Data from 9,778 adults who participated in the Korea National Health and Nutrition Examination Survey (KNHANES) in 2014 and 2016 were analyzed. The estimated glomerular filtration rate was calculated using the CKD Epidemiology Collaboration (CKD EPI) equation. Depression was defined as a score of at least 10 points on Patient Health Questionnaire-9 (PHQ-9). The HRQOL was measured using the EuroQol-5D (EQ-5D). The effects of CKD on depression were analyzed using multivariate logistic regression, and the effects on perceived health and HRQOL were analyzed using multivariate ordered logistic regression.

Results: The prevalence of CKD was 3.7%. Among the adults with CKD, 13.1% had depression, 42.9% perceived their health to be bad, and their HRQOL was significantly lower than that of their non-CKD counterparts. The odds ratio for depression in patients with CKD was 1.66 (95% Confidence Interval [CI]=1.10~2.52, p=.017) and that of perceived bad or fair health was 1.80 (95% CI=1.35~2.40, p<.001). The likelihood of lower HRQOL in CKD patients was 1.44 times higher than in the non-CKD patients (95% CI=1.09~1.90, p=.010).

Conclusion: The prevalence of psychological problems in CKD patients was higher than in non-CKD patients. The results suggest the importance of comprehensive intervention for patients with CKD. Policies are needed to help assess and manage patients with CKD who are experiencing emotional problems.
KEYWORD
Chronic kidney disease, Depression, Subjective health, Quality of life
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